Orthobiologic Injections
The broad field of injectable therapies focuses on stimulating healing in injured tissue and recruiting the body's self-repair cells.
About This Research Area
Orthobiologic injections offer a powerful non-operative approach to joint injuries. SRF is leading a head-to-head study to determine which of these therapies offers the most effective and lasting relief from joint pain and inflammation.
Current injectables remain inadequate. Cortisone, the most common injection, may reduce symptoms in the short term, but degrades tissue and increases the risk of complications over time. Orthobiologic injections present a promising, regenerative approach—but the field has yet to establish which injectables offer the most significant, lasting benefit. We believe that patients deserve regenerative therapies that truly deliver the best outcomes.
To achieve this future, we are conducting a comprehensive trial of orthobiologic injections in partnership with Daniel Grande, PhD, President of the International Cartilage Research Society (ICRS) and Director of Orthopaedic Research at The Feinstein Institutes for Medical Research. This study will compare leading joint pain injections to determine which is safest and most effective.
Research Currently Underway
Our research program is actively investigating new biologic solutions for joint restoration.
Areas of Investigation
Platelet-Rich Plasma (PRP)
Concentrated growth factors from the patient’s own blood to accelerate tissue repair.
Sources Mesenchymal Stromal Cells (MSCs)
MSCs are quasi-stem cells that are naturally found in the bone marrow and adipose tissue (fat tissue).
Current Research Projects
Through our outcome studies and collaborations, our research team is actively investigating new approaches in orthobiologic injections to better understand how biologic therapies may support healing, reduce inflammation, and improve outcomes for patients with sports injuries and arthritis. New updates will be shared here.
Patient Stories
Patient outcomes and stories related to injection therapies.
Published Research
As research findings are published, they will be added to this library to share our scientific advancements with researchers, patients, and the broader SRF community.
Support This Research
Help us develop new biologic solutions for people who want to stay active after injury or arthritis.